NOTCH1 mutation
Showing 1 - 25 of 7,052
Adenoid Cystic Carcinoma, Metastatic Adenoid Cystic Carcinoma, Recurrent Adenoid Cystic Carcinoma Trial in Boston (CB-103,
Not yet recruiting
- Adenoid Cystic Carcinoma
- +2 more
- CB-103
- +2 more
-
Boston, MassachusettsDana Farber Cancer Institute
Mar 14, 2023
Natural History Study of CADASIL
Recruiting
- Cardiovascular Disease
- +4 more
-
Bethesda, MarylandNational Institutes of Health Clinical Center
Oct 29, 2022
Autosomal Dominant Optic Atrophy (ADOA), Caused by OPA1 Mutation
Not yet recruiting
- Autosomal Dominant Optic Atrophy
- +3 more
-
Sydney, AustraliaSydney Eye Hospital
Nov 15, 2023
An Intervention to Increase Genetic Testing in Families Who May
Recruiting
- BRCA1 Mutation
- +21 more
- Intervention Arm At-risk Relative/ARR Contacts
- +5 more
-
Basking Ridge, New Jersey
- +7 more
Nov 22, 2022
Solid Tumor, ARID1A Gene Mutation Trial in Greenville (Tazemetostat)
Suspended
- Solid Tumor
- ARID1A Gene Mutation
-
Greenville, South CarolinaPrisma Health Cancer Institute
Jan 10, 2023
Metastatic Solid Tumor, SF3B1 Gene Mutation, Spliceosome Mutation Trial in Baltimore (Recommendation for treatment with
Recruiting
- Metastatic Solid Tumor
- +4 more
- Recommendation for treatment with immunotherapy
-
Baltimore, MarylandJohns Hopkins University
Sep 8, 2022
Cholangiocarcinoma Non-resectable, Cholangiocarcinoma Metastatic Trial (Ivosidenib)
Not yet recruiting
- Cholangiocarcinoma Non-resectable
- Cholangiocarcinoma Metastatic
- (no location specified)
Oct 10, 2023
Non Small Cell Lung Cancer, Immune Checkpoint Inhibitor, EGFR Exon 21 Mutation Trial in Peking (Pembrolizumab, pemetrexed,
Not yet recruiting
- Non Small Cell Lung Cancer
- +2 more
- Pembrolizumab, pemetrexed, platinum
- Osimertinib
-
Peking, ChinaPeking Union Medical College Hospital
Nov 16, 2023
Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression = 1% and an STK11
Recruiting
- Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation
-
Montpellier, France
- +7 more
Dec 19, 2022
Advanced Malignant Solid Tumor, EGFR Gene Amplification, EGFR Gene Mutation Trial in Houston (Everolimus, Neratinib,
Recruiting
- Advanced Malignant Solid Neoplasm
- +9 more
- Everolimus
- +3 more
-
Houston, TexasM D Anderson Cancer Center
Oct 25, 2022
Retinal Dystrophy, PRPF31 Mutationassociated Retinal Dystrophy, RP11 Trial in Dallas (VP-001)
Recruiting
- Retinal Dystrophy
- +2 more
-
Dallas, TexasRetina Foundation of the Southwest
Jun 5, 2023
NSCLC Metastatic Trial in Stockholm (Stereotactic body radiation therapy (SBRT), Temporary Stopping)
Recruiting
- Non-small Cell Lung Cancer Metastatic
- Stereotactic body radiation therapy (SBRT)
- Temporary Stopping
-
Stockholm, Solna, SwedenKarolinska University Hospital
Nov 9, 2023
Does Notch Regulate Glioma Proliferation ?
Completed
- Glioma
-
Montpellier, FranceUhmontpellier
Mar 18, 2021
Breast Cancer, Genetic Predisposition Trial in Rome, Varese (Genetic predisposition to breast cancer)
Recruiting
- Breast Cancer
- Genetic Predisposition
- Genetic predisposition to breast cancer
-
Rome, Italy
- +1 more
May 4, 2023
BRCA1/2 Flu Vaccine
Active, not recruiting
- BRCA1 Mutation
- BRCA2 Mutation
- Seasonal influenza vaccine
-
Philadelphia, PennsylvaniaUniversity of Pennsylvania
Aug 16, 2022
Desmoid Tumor, NOTCH Gene Mutation Positive Tumors Trial (Nirogacestat (Gamma Secretase Inhibitor))
Available
- Desmoid Tumor
- NOTCH Gene Mutation Positive Tumors
- Nirogacestat (Gamma Secretase Inhibitor)
- (no location specified)
Sep 7, 2021
BRCA1 Gene Mutation, BRCA2 Gene Mutation, Ovarian Serous Adenocarcinoma Trial in Buffalo, New York (biological, other, drug)
Active, not recruiting
- BRCA1 Gene Mutation
- +5 more
- Durvalumab
- +3 more
-
Buffalo, New York
- +1 more
Jan 20, 2023
Recurrent IDH1/2 Mutated Glioma Trial in Paris (Azacitidine)
Recruiting
- Recurrent IDH1/2 Mutated Glioma
-
Paris, FrancePitie Salpetriere Hospital
Aug 29, 2022
